The CD25 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to IL2R, IL2RA, and Ly-43. This antibody recognizes Human antigen. The CD25 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta
(IL2RB) chains, together with the common gamma chain (IL2RG),
constitute the high-affinity IL2 receptor. Homodimeric alpha chains
(IL2RA) result in low-affinity receptor, while homodimeric beta
(IL2RB) chains produce a medium-affinity receptor. Normally an
integral-membrane protein, soluble IL2RA has been isolated and
determined to result from extracellular proteolyisis.
Alternately-spliced IL2RA mRNAs have been isolated, but the
significance of each is presently unknown. Mutations in this gene
are associated with interleukin 2 receptor alpha
deficiency